2009, discovery of a fresh phenotype for microorganisms in slim nanofluidic slits; and initially detection of nearby protein structures along DNA making use of sound-condition nanopores
You often get involved in conversations about science and faith. You have got also prepared a number of guides on the subject. Don’t you believe eventually we will know anything and that God’s purpose will likely be over?
Multicolor imaging in the bacterial nucleoid and cell division proteins with blue, orange, and in close proximity to-infrared fluorescent proteins
Our get the job done was immediately adopted up by others, most notably by Phaedon Avouris and colleagues at IBM, who in October 1998 published their findings on transistors produced from single- and multi-walled carbon nanotubes in Applied Physics Letters.
This yielded a breakthrough. Within just a few months, we were ready to measure transportation via somebody single-walled carbon nanotube. Dependant on minimal-temperature experiments by a superb PhD college student in my team, Sander Tans (now a valued colleague and professor at Delft University of Technology using an Lively analysis lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes had been authentic quantum wires with extremely very long (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic behaviour.
Our exploration ranges with the biophysics of DNA to artificial cells and outside of. Remember to have a look beneath on the spectrum of our existing tasks.
We use nanofabricated microfluidic constructions to pattern spatial boundaries for microorganisms and biomimetic vesicles with reconstituted protein networks and this assess the fundamental role of spatial confinement at the molecular and cellular amount. Our projects include the subsequent:
Dynamic ParB–DNA interactions initiate and retain a partition condensate for bacterial chromosome segregation
‘Yes, I fully grasp people ended up surprised at time. At the conclusion of the nineties, when I was in my forties, I used to be Professor of Molecular Electronics and I've to admit that it had turn into a little bit bored, I didn’t understand much any more. The sphere went more into the appliance facet, how you can integrate nanotubes into Digital circuits.
Resolving the phase dimensions in condensin-pushed DNA loop extrusion identifies ATP binding as being the move-making system
An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes
1999, first measurement with the wavefunction of single molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for a new Luttinger description of interacting electrons in nanotubes
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It absolutely was an incredibly fascinating time, for the duration of which I received a https://www.ceesdekker.net great deal of aid from Delft University of Know-how, exactly where I used to be a professor at some time, and I commenced quite a few collaborations with molecular biologists. That helped me understand a lot.’